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Journal of Computational Biology
Mining the Biomedical Literature in the Genomic Era: An Overview

To cite this article:
Hagit Shatkay, Ronen Feldman. Journal of Computational Biology. December 2003, 10(6): 821-855. doi:10.1089/106652703322756104.

Published in Volume: 10 Issue 6: July 5, 2004

Full Text: • PDF for printing (626 KB) • PDF w/ links (543.9 KB)


Hagit Shatkay
School of Computing, Queen's University, Kingston, Ontario, Canada K7L3N6
Ronen Feldman
Department of Computer Science, Bar Ilan University, Ramat Gan 52900, Israel

The past decade has seen a tremendous growth in the amount of experimental and computational biomedical data, specifically in the areas of genomics and proteomics. This growth is accompanied by an accelerated increase in the number of biomedical publications discussing the findings. In the last few years, there has been a lot of interest within the scientific community in literature-mining tools to help sort through this abundance of literature and find the nuggets of information most relevant and useful for specific analysis tasks. This paper provides a road map to the various literature-mining methods, both in general and within bioinformatics. It surveys the disciplines involved in unstructured-text analysis, categorizes current work in biomedical literature mining with respect to these disciplines, and provides examples of text analysis methods applied towards meeting some of the current challenges in bioinformatics.

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