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Journal of Computational Biology
Mining the Biomedical Literature in the Genomic Era: An Overview
To cite this article:
Hagit Shatkay, Ronen Feldman.
Journal of Computational Biology.
December 2003,
10(6): 821-855.
doi:10.1089/106652703322756104.
Published in Volume: 10 Issue 6: July 5, 2004
Hagit Shatkay School of Computing, Queen's University, Kingston, Ontario, Canada K7L3N6 Ronen Feldman Department of Computer Science, Bar Ilan University, Ramat Gan 52900, Israel The past decade has seen a tremendous growth in the amount of experimental and computational biomedical data, specifically in the areas of genomics and proteomics. This growth is accompanied by an accelerated increase in the number of biomedical publications discussing the findings. In the last few years, there has been a lot of interest within the scientific community in literature-mining tools to help sort through this abundance of literature and find the nuggets of information most relevant and useful for specific analysis tasks. This paper provides a road map to the various literature-mining methods, both in general and within bioinformatics. It surveys the disciplines involved in unstructured-text analysis, categorizes current work in biomedical literature mining with respect to these disciplines, and provides examples of text analysis methods applied towards meeting some of the current challenges in bioinformatics.  This paper was cited by:SENT: semantic features in text M. Vazquez, P. Carmona-Saez, R. Nogales-Cadenas, M. Chagoyen, F. Tirado, J. M. Carazo, A. Pascual-Montano Nucleic Acids Research. Aug 2009, Vol. 37, No. Web Server: W153-W159 CrossRef Evaluation of genome-wide association study results through development of ontology fingerprints L. C. Tsoi, M. Boehnke, R. L. Klein, W. J. Zheng Bioinformatics. Jun 2009, Vol. 25, No. 10: 1314-1320 CrossRef Bioinformatic Analysis Reveals cRel as a Regulator of a Subset of Interferon-Stimulated Genes Lai Wei, Meiyun Fan, Lijing Xu, Kevin Heinrich, Michael W. Berry, Ramin Homayouni, Lawrence M. Pfeffer Journal of Interferon & Cytokine Research. Sep 2008, Vol. 28, No. 9: 541-552 Abstract | Full Text PDF | Reprints & PermissionsCategorization of services for seeking information in biomedical literature: a typology for improvement of practice J.-j. Kim, D. Rebholz-Schuhmann Briefings in Bioinformatics. Aug 2008, Vol. 9, No. 6: 452-465 CrossRef Kernel-based learning for biomedical relation extraction Jiexun Li, Zhu Zhang, Xin Li, Hsinchun Chen Journal of the American Society for Information Science and Technology. Apr 2008, Vol. 59, No. 5: 756-769 CrossRef Comparison of full-text searching to metadata searching for genes in two biomedical literature cohorts Bradley M. Hemminger, Billy Saelim, Patrick F. Sullivan, Todd J. Vision Journal of the American Society for Information Science and Technology. Jan 2008, Vol. 58, No. 14: 2341-2352 CrossRef A Cheminformatic Toolkit for Mining Biomedical Knowledge Gus R. Rosania, Gordon Crippen, Peter Woolf, David States, Kerby Shedden Pharmaceutical Research. Sep 2007, Vol. 24, No. 10: 1791-1802 CrossRef Gleaner: Creating ensembles of first-order clauses to improve recall-precision curves Mark Goadrich, Louis Oliphant, Jude Shavlik Machine Learning. Oct 2006, Vol. 64, No. 1-3: 231-261 CrossRef Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project Marcin Adamski, Thomas Blackwell, Rajasree Menon, Lennart Martens, Henning Hermjakob, Chris Taylor, Gilbert  S. Omenn, David  J. States PROTEOMICS. Sep 2005, Vol. 5, No. 13: 3246-3261 CrossRef Microbial metabolomics: replacing trial-and-error by the unbiased selection and ranking of targets Mariët J. van der Werf, Renger H. Jellema, Thomas Hankemeier Journal of Industrial Microbiology & Biotechnology. Jul 2005, Vol. 32, No. 6: 234-252 CrossRef Word Sense Disambiguation in the Biomedical Domain: An Overview Martijn J. Schuemie, Jan A. Kors, Barend Mons Journal of Computational Biology. Jun 2005, Vol. 12, No. 5: 554-565 Abstract | Full Text PDF | Reprints & PermissionsInformation problems in molecular biology and bioinformatics W. John MacMullen, Sheila O. Denn Journal of the American Society for Information Science and Technology. Apr 2005, Vol. 56, No. 5: 447-456 CrossRef
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