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Human Gene Therapy
A Phase I Clinical Trial of Lethally Irradiated Allogeneic Pancreatic Tumor Cells Transfected with the GM-CSF Gene for the Treatment of Pancreatic Adenocarcinoma. The Johns Hopkins Oncology Center, Baltimore, Maryland
To cite this paper:
Elizabeth M. Jaffee, Ross Abrams, John Cameron, Ross Donehower, Mary Duerr, Jeanette Gossett, Tim F. Greten, Louise Grochow, Ralph Hruban, Scott Kern, Keith D. Lillemoe, Seamus O'Reilly, Drew Pardoll, Henry A. Pitt, Patricia Sauter, Christine Weber, Charles Yeo.
Human Gene Therapy.
September 1, 1998,
9(13): 1951-1971.
doi:10.1089/hum.1998.9.13-1951.
Principal Investigator Elizabeth M. Jaffee, M.D.Department of Oncology, Johns Hopkins University School of Medicine, Ross Building, Room 350, 720 Rutland Avenue, Baltimore, MD 21205, Telephone: 410-955-2957, FAX: 410-614-8216. E-mail: ejaffee@welchlink.welch.jhu.edu Co-Investigators Ross Abrams, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 John Cameron, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Ross Donehower, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Mary Duerr The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Jeanette Gossett, B.S.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Tim F. Greten, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Louise Grochow, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Ralph Hruban, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Scott Kern, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Keith D. Lillemoe, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Seamus O'Reilly, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Drew Pardoll, M.D., Ph.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Henry A. Pitt, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Patricia Sauter, R.N.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Christine Weber, R.N.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509 Charles Yeo, M.D.The Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, Maryland 21287-7509  This paper was cited by:A Phase I Vaccine Safety and Chemotherapy Dose-Finding Trial of an Allogeneic GM-CSF–Secreting Breast Cancer Vaccine Given in a Specifically Timed Sequence with Immunomodulatory Doses of Cyclophosphamide and Doxorubicin. The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland Human Gene Therapy. Mar 2004, Vol. 15, No. 3: 313-337 Citation | Full Text PDFCCL3/MIP-1α Is a Potent Immunostimulator When Coexpressed with Interleukin-2 or Granulocyte-Macrophage Colony-Stimulating Factor in a Leukemia/Lymphoma Vaccine Andree Zibert, Stefan Balzer, Manfred Souquet, Trong Hung Quang, Cristina Paris-Scholz, Marie Roskrow, Dagmar Dilloo Human Gene Therapy. Jan 2004, Vol. 15, No. 1: 21-34 Abstract | Full Text PDF | Reprints & PermissionsImmunization by Particle-Mediated Transfer of the Granulocyte-Macrophage Colony-Stimulating Factor Gene into Autologous Tumor Cells in Melanoma or Sarcoma Patients: Report of a Phase I/IB Study D.M. Mahvi, F.-S. Shi, N.-S. Yang, S. Weber, J. Hank, M. Albertini, J. Schiller, H. Schalch, M. Larson, L. Pharo, J. Gan, D. Heisey, T. Warner, P.M. Sondel Human Gene Therapy. Sep 2002, Vol. 13, No. 14: 1711-1721 Abstract | Full Text PDF | Reprints & PermissionsCombination of CD80 and Granulocyte-Macrophage Colony-Stimulating Factor Coexpression by a Leukemia Cell Vaccine: Preclinical Studies in a Murine Model Recapitulating Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia R. Stripecke, D.C. Skelton, P.K. Pattengale, H. Shimada, D.B. Kohn Human Gene Therapy. Sep 1999, Vol. 10, No. 13: 2109-2122 Abstract | Full Text PDF | Reprints & Permissions |
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